4-Chloro-2-(trifluoromethyl)benzyl bromide → 1-(4-Chloro-2-trifluoromethyl-benzyl)-3-methyl-1H-indazole-5-carbaldehyde

HRID 1949514노트

반응식

HRID 1949514 반응식
[CH3:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH:11]=[O:12])[CH:9]=2)[NH:4][N:3]=1.Br[CH2:14][C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:16]=1[C:22]([F:25])([F:24])[F:23]>>[Cl:21][C:18]1[CH:19]=[CH:20][C:15]([CH2:14][N:4]2[C:5]3[C:10](=[CH:9][C:8]([CH:11]=[O:12])=[CH:7][CH:6]=3)[C:2]([CH3:1])=[N:3]2)=[C:16]([C:22]([F:23])([F:24])[F:25])[CH:17]=1

참가 물질

3

반응물 2

HCID 34925974-Chloro-2-(trifluoromethyl)benzyl bromideHCID 178434286HCID 178434286, 화합물

생성물 1

HCID 866545911-(4-Chloro-2-trifluoromethyl-benzyl)-3-methyl-1H-indazole-5-carbaldehyde

실험 절차

1-(4-Chloro-2-trifluoromethyl-benzyl)-3-methyl-1H-indazole-5-carbaldehyde was prepared from 3-Methyl-1H-indazole-5-carbaldehyde and 1-Bromomethyl-4-chloro-2-trifluoromethyl-benzene following general procedure A.

출처 및 근거

ORD 기록
ord-abc04388133f43bbb74d0f381decd57a
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399681B2

반응 노트

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