2-(Chloromethyl)-3-(trifluoromethyl)pyridine → 1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde

HRID 1949605노트

반응식

HRID 1949605 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1.Cl[CH2:13][C:14]1[C:19]([C:20]([F:23])([F:22])[F:21])=[CH:18][CH:17]=[CH:16][N:15]=1>>[F:23][C:20]([F:21])([F:22])[C:19]1[C:14]([CH2:13][N:1]2[C:9]3[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=3)[CH:3]=[N:2]2)=[N:15][CH:16]=[CH:17][CH:18]=1

참가 물질

3

반응물 2

HCID 183617372-(Chloromethyl)-3-(trifluoromethyl)pyridineHCID 212506441H-Indazole-5-carboxaldehyde

생성물 1

HCID 866546281-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde

실험 절차

1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde was prepared from 1H-Indazole-5-carbaldehyde and 2-Chloromethyl-3-trifluoromethyl-pyridine following General Procedure A.

출처 및 근거

ORD 기록
ord-0a66159cd68645bf9025b30480ae3241
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399681B2

반응 노트

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