Benzyl Alcohol → Benzyl 4-carboxyphenylacetate

HRID 1950653노트

반응식

HRID 1950653 반응식
C(C1C=CC(CC(O)=O)=CC=1)=[O:2].C(O)C1C=CC=CC=1.[CH:21]([C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30]([O:32][CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)=[O:31])=[CH:25][CH:24]=1)=[O:22]>>[CH2:33]([O:32][C:30]([CH2:29][C:26]1[CH:25]=[CH:24][C:23]([C:21]([OH:2])=[O:22])=[CH:28][CH:27]=1)=[O:31])[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

참가 물질

4

반응물 3

HCID 244Benzyl AlcoholHCID 113441872-(4-formylphenyl)acetic AcidHCID 19966221Benzyl 2-(4-formylphenyl)acetate

생성물 1

HCID 19966080Benzyl 4-carboxyphenylacetate수율 80.6%

실험 절차

Synthesized from (4-formylphenyl)acetic acid (1 g) and benzyl alcohol (730 mg) according to an analogous synthetic method to Example 806, benzyl (4-formylphenyl)acetate (1.4 g) was used according to an analogous synthetic method to Preparation Example 53 to provide the title compound (1.2 g).

후처리

  1. customwas used according to an analogous synthetic method to Preparation Example 53

출처 및 근거

ORD 기록
ord-c45b78abdee74abfaacf72d90fd3e6ec
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08399520B2

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