참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydroxylamine | HCID 787 | — |
| 반응물 | 2-Ethoxybenzonitrile | HCID 576922 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-ethoxy-N'-hydroxybenzenecarboximidamide | HCID 4056736 | 97.2% |
반응 단계
Hydroxylamine (Fluka 55458; 50% in water; 4.08 mL; 67.95 mmol; 5 eq.) was added to a solution of 2-ethoxybenzonitrile (Fluorochem 18661; 2 g; 13.59 mmol; 1 eq.) in EtOH (30 mL) and the reaction mixture was stirred at 50° C. for 12 hours. Evaporation in vacuo gave a white solid, which was further dried under high vacuum to afford the title compound (2.38 g, 97%) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08404676B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_03 |
|---|
| ORD ID | ord-221697abe7f944b09464f196de649a4e |
|---|
| 출처 메모 | uspto-grants-2013_03 |
|---|
