Aniline → 7-(2-Fluoro-pyrimidin-4-yl)-2,6,8-trimethyl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one

HRID 1951247노트

반응식

HRID 1951247 반응식
[F:1][C:2]1[N:7]=[C:6]([C:8]2[C:9]([CH3:19])=[C:10]3[C:15](=[O:16])[NH:14][CH2:13][CH2:12][N:11]3[C:17]=2[CH3:18])[CH:5]=[CH:4][N:3]=1.N[C:21]1C=CC=CC=1>>[F:1][C:2]1[N:7]=[C:6]([C:8]2[C:9]([CH3:19])=[C:10]3[C:15](=[O:16])[N:14]([CH3:21])[CH2:13][CH2:12][N:11]3[C:17]=2[CH3:18])[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 6115AnilineHCID 591857897-(2-fluoropyrimidin-4-yl)-6,8-dimethyl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one

생성물 1

HCID 670227867-(2-Fluoro-pyrimidin-4-yl)-2,6,8-trimethyl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one

실험 절차

The following compounds were prepared by reaction of 7-(2-fluoropyrimidin-4-yl)-6,8-dimethyl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one with an the appropriate aniline

출처 및 근거

ORD 기록
ord-9306f82f015f4e65aea39d1996408ef9
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08404692B2

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