7-(2-fluoropyrimidin-4-yl)-6,8-dimethyl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one → HCID 178422088, 화합물

HRID 1951248노트

반응식

HRID 1951248 반응식
F[C:2]1[N:7]=[C:6]([C:8]2[C:9]([CH3:19])=[C:10]3[C:15](=[O:16])[NH:14][CH2:13][CH2:12][N:11]3[C:17]=2[CH3:18])[CH:5]=[CH:4][N:3]=1.[NH:20]1[C:24]([C:25]2[CH:30]=[CH:29][C:28]([NH2:31])=[CH:27][CH:26]=2)=[N:23][N:22]=[N:21]1>>[CH3:18][C:17]1[N:11]2[CH2:12][CH2:13][NH:14][C:15](=[O:16])[C:10]2=[C:9]([CH3:19])[C:8]=1[C:6]1[CH:5]=[CH:4][N:3]=[C:2]([NH:31][C:28]2[CH:29]=[CH:30][C:25]([C:24]3[NH:23][N:22]=[N:21][N:20]=3)=[CH:26][CH:27]=2)[N:7]=1

참가 물질

3

반응물 2

HCID 591857897-(2-fluoropyrimidin-4-yl)-6,8-dimethyl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-oneHCID 178507471HCID 178507471, 화합물

생성물 1

HCID 178422088HCID 178422088, 화합물

실험 절차

Prepared by reaction of 7-(2-fluoropyrimidin-4-yl)-6,8-dimethyl-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one with 4-(1H-tetrazol-5-yl)-phenylamine.

출처 및 근거

ORD 기록
ord-534e0e99538b4af9ba88f85eee60c4f9
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08404692B2

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