4-Formyl-3-vinylbenzonitrile → 3-Ethyl-4-formylbenzonitrile

HRID 1951383노트

반응식

HRID 1951383 반응식
[CH:1]([C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][C:4]=1[CH:11]=[CH2:12])=[O:2]>C(O)C.[Pd]>[CH2:11]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:3]=1[CH:1]=[O:2])[C:7]#[N:8])[CH3:12]

참가 물질

4

반응물 1

HCID 540496494-Formyl-3-vinylbenzonitrile

생성물 1

HCID 178193273-Ethyl-4-formylbenzonitrile

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 1.3 g (8.27 mmol) of 4-formyl-3-vinylbenzonitrile in 35 ml of ethanol is mixed with 880 mg of 10% palladium on carbon and vigorously stirred under a hydrogen atmosphere for 2 h. The suspension is filtered through a layer of kieselguhr, the residue is washed with ethanol, and the filtrate is concentrated. The residue (890 mg) is employed without further purification in the following stage.

후처리

  1. filtrationThe suspension is filtered through a layer of kieselguhr
  2. washthe residue is washed with ethanol
  3. concentrationthe filtrate is concentrated
  4. customThe residue (890 mg) is employed without further purification in the following stage

출처 및 근거

ORD 기록
ord-5961038d2ff14dfcb0fe4c3b12a1ab8c
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08404709B2

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