Potassium Carbonate → HCID 15490947, 화합물

HRID 1953081노트

반응식

HRID 1953081 반응식
[CH3:1][C:2]1[NH:3][C:4](=[O:9])[CH:5]=[C:6]([CH3:8])[N:7]=1.Br[CH2:11][CH2:12][O:13][C:14]1[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][CH:15]=1.C([O-])([O-])=O.[K+].[K+]>>[CH3:1][C:2]1[N:3]([CH2:11][CH2:12][O:13][C:14]2[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][CH:15]=2)[C:4](=[O:9])[CH:5]=[C:6]([CH3:8])[N:7]=1

참가 물질

4

반응물 3

HCID 11430Potassium CarbonateHCID 2627064-(2-Bromoethoxy)BenzaldehydeHCID 1354086402,6-Dimethyl-1H-pyrimidin-4-one

생성물 1

HCID 15490947HCID 15490947, 화합물수율 30%

실험 절차

The title compound (0.8 g, 30%) was prepared from 2,4-dimethyl-1,6-dihydro-6-pyrimidone (1.3 g, 10.48 mmol) and 4-[2-bromoethoxy]benzaldehyde (2,4 g, 10.48 mmol) in the presence of a base K2CO3 (2.89 g, 20.96 mmol) by a similar procedure as described in preparation 1.

후처리

  1. customas described in preparation 1

출처 및 근거

ORD 기록
ord-73f4927f9b2f44de83565a56f7abe556
출처 데이터셋
uspto-grants-2000_09
특허 번호
US06114526

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