3-Quinuclidinyl butyrate → (R)-quinuclidinol

HRID 1953938

반응식

HRID 1953938 반응식
C(O[CH:7]1[CH:12]2[CH2:13][CH2:14][N:9]([CH2:10][CH2:11]2)[CH2:8]1)(=O)CCC.[OH2:15].[OH-].[Na+]>>[N:9]12[CH2:14][CH2:13][CH:12]([CH2:11][CH2:10]1)[CH2:7][C@H:8]2[OH:15]

참가 물질

3

반응물 2

HCID 100585403-Quinuclidinyl butyrateHCID 23719242Sodium hydroxide--water (1/1/1)

생성물 1

HCID 53816262(R)-quinuclidinol

실험 절차

The resulting (R) 3-quinuclidinyl butyrate was hydrolyzed with water-NaOH and then recrystallized from toluene to give (R)-quinuclidinol. Specific rotation [α]24D =-45 (1N HCl).

후처리

  1. customrecrystallized from toluene

출처 및 근거

ORD 기록
ord-0deff05d10824556afa0ce95b89ed9fd
출처 데이터셋
uspto-grants-2000_09
특허 번호
US06121025

연결된 노트

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