Dichlorodimethylsilane → Dimethyl(2-methylindenyl)silyl chloride

HRID 1953958노트

반응식

HRID 1953958 반응식
[CH3:1][Si:2]([CH3:5])(Cl)[Cl:3].O1CCCC1.[CH3:11][C:12]1[CH:13]([Li])[C:14]2[C:19]([CH:20]=1)=[CH:18][CH:17]=[CH:16][CH:15]=2>CCCCCC>[CH3:1][Si:2]([Cl:3])([CH3:5])[CH:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:20]=[C:12]1[CH3:11]

참가 물질

5

반응물 3

HCID 6398DichlorodimethylsilaneHCID 8028TetrahydrofuranHCID 178506826HCID 178506826, 화합물

생성물 1

HCID 21943870Dimethyl(2-methylindenyl)silyl chloride수율 58%

시약·촉매·용매 1

HCID 8058Hexane용매

실험 절차

In a three-necked flask equipped with a mechanical stirrer were charged 44.5 g (345 mmol) of dimethyldichlorosilane, 300 ml of tetrahydrofuran and n-hexane, to which was added at -78° C. a 2-methylindenyllithium solution, followed by stirring at room temperature for 3 hours. After the solvent was distilled off under reduced pressure, 100 ml of hexane was added and insoluble matter was removed by centrifugation. After the solvent was distilled off under reduced pressure, distillation under reduced pressure (113° C./7mmHg) afforded 14.9 g (67 mmol, yield: 58%) of dimethyl(2-methylindenyl)silyl chloride as a pale yellow liquid.

후처리

  1. customIn a three-necked flask equipped with a mechanical stirrer
  2. distillationAfter the solvent was distilled off under reduced pressure, 100 ml of hexane
  3. additionwas added
  4. custominsoluble matter was removed by centrifugation
  5. distillationAfter the solvent was distilled off under reduced pressure, distillation under reduced pressure (113° C./7mmHg)

출처 및 근거

ORD 기록
ord-ae69011f711b4342ba0c54b65629a3c9
출처 데이터셋
uspto-grants-2000_09
특허 번호
US06121182

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