Indole-3-Butyric Acid → 3-Indolyl-butyramide

HRID 1954226노트

반응식

HRID 1954226 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[CH2:10][CH2:11][C:12]([NH2:14])=[O:13].N1C2C(=CC=CC=2)C(CCCC(O)=O)=[CH:16]1.C(N1C=CN=C1)(N1C=CN=C1)=O>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[CH:10]([CH3:16])[CH2:11][C:12]([NH2:14])=[O:13]

참가 물질

4

반응물 3

HCID 8617Indole-3-Butyric AcidHCID 682631,1'-CarbonyldiimidazoleHCID 21703095HCID 21703095, 화합물

생성물 1

HCID 217030923-Indolyl-butyramide수율 96%

실험 절차

This compound was prepared in the manner described above for (18a), using 3-indolebutyric acid and 1,1'-carbonyldimidazole. A 96% yield was obtained as a off-white solid: mp 86-87° C.

후처리

  1. customThis compound was prepared in the manner
  2. customA 96% yield was obtained as a off-white solid

출처 및 근거

ORD 기록
ord-249859463c734e24ac4a0f36d77fc5ed
출처 데이터셋
uspto-grants-2000_09
특허 번호
US06121307

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