Ammonia → 6-Aminohexanenitrile

HRID 1954487노트

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HRID 1954487 반응식
[CH:1]([CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[N:8])=O.[NH3:9]>[H][H]>[NH2:9][CH2:1][CH2:3][CH2:4][CH2:5][CH2:6][C:7]#[N:8].[NH2:9][CH2:1][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][NH2:8]

참가 물질

5

반응물 2

HCID 222AmmoniaHCID 110406526-Oxohexanenitrile

생성물 2

HCID 16402Hexamethylenediamine수율 12%HCID 170796-Aminohexanenitrile수율 73%

시약·촉매·용매 1

HCID 178418361HCID 178418361, 화합물용매2회

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온도
80 °C

실험 절차

In an autoclave having a capacity of 300 ml and equipped with a sampling sluice (material HC 4) there were placed 11 g of 5-formylvaleronitrile and 3 g of Ru (3%) on Al2O3 (4 mm extrudates) under protective gas (argon). The autoclave was then sealed and 150 ml of NH3 were forced in. Thorough mixing was effected using a magnetic stirrer. After heating to 80° C. (autogenous pressure: ca. 39 bar) the mixture was kept at 80° C. for a further 2 hours and then the overall pressure was raised, with hydrogen, to 70 bar. The pressure of 70 bar was maintained by constantly forcing in more hydrogen. After 25 hours, the autoclave was depressurized and the hydrogenation effluent analyzed by gas chromatography. The products formed comprised 73% of 6-aminocapronitrile and 12% of hexamethylene diamine. The conversion was 100%.

후처리

  1. customequipped with a sampling sluice (material HC 4) there
  2. customThe autoclave was then sealed
  3. additionThorough mixing
  4. temperatureThe pressure of 70 bar was maintained
  5. waitAfter 25 hours

출처 및 근거

ORD 기록
ord-63d24e8db18247ac85c4af57ca8484bc
출처 데이터셋
uspto-grants-2000_09
특허 번호
US06121481

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