HCID 54512044, 화합물 → 1-Propanol, 3,3,3-trifluoro-, 1-acetate

반응식

[C:1]([O:4][CH:5]=[CH:6][C:7]([F:10])([F:9])[F:8])(=[O:3])[CH3:2]>[Pd]>[C:7]([CH2:6][CH2:5][O:4][C:1]([CH3:2])=[O:3])([F:10])([F:9])[F:8]

참가 물질

실험 절차

3,3,3-Trifluoropropenyl acetate (7.1. g) was hydrogenated in a glass pressure bottle overnight at 65°-70° C. using 0.1 g 10% Pd/C as catalyst and a maximum H2 pressure of 35 psi. The catalyst was separated by centrifugation, providing 6.7 g of 97% pure CF3CH2CH2OAc (93% yield). Bp 112°-113° C. [lit. 112° C.; B. T. Golding, P. J. Sellars, and W. P. Watson, J. Fluorine Chem., 30 (1985) 153]. 1H NMR: δ4.29 (t, 2 H, J=6.4 Hz), 2.4 (m, 2 H), 2.07 (s, 3H). 19F NMR: δ-65.8 (t, J=10.4 Hz).

후처리

customwas hydrogenated in a glass pressure bottle overnight at 65°-70° C.
customThe catalyst was separated by centrifugation

출처 및 근거

ORD 기록: ord-44d7a08e22f94c73be955801c289b26a
출처 데이터셋: uspto-grants-1998_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05777184

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참가 물질

반응물 1

HCID 54512044HCID 54512044, 화합물

생성물 1

HCID 134949291-Propanol, 3,3,3-trifluoro-, 1-acetate수율 93%

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

후처리

customwas hydrogenated in a glass pressure bottle overnight at 65°-70° C.
customThe catalyst was separated by centrifugation

출처 및 근거

ORD 기록: ord-44d7a08e22f94c73be955801c289b26a
출처 데이터셋: uspto-grants-1998_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05777184

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