1-Isocyanato-2-phenylbenzene → N-(2-hydroxy 4-carbomethoxyphenyl) N'-(2-phenylphenyl)urea

HRID 1956649

반응식

HRID 1956649 반응식
[OH:1][C:2]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[C:13]1([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=2[N:25]=[C:26]=[O:27])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[OH:1][C:2]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:26]([NH:25][C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:27]

참가 물질

3

반응물 2

HCID 2222801-Isocyanato-2-phenylbenzeneHCID 7020619Benzoic acid, 4-amino-3-hydroxy-, methyl ester

생성물 1

HCID 22011340N-(2-hydroxy 4-carbomethoxyphenyl) N'-(2-phenylphenyl)urea수율 51.1%

실험 절차

The urea was prepared from 2-hydroxy 4-carbomethoxy aniline(0.167 g, 1 mmol) and 2-phenyl phenyl isocyanate(1 mmol) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the desired compound(0.185 g, 50%). EI-MS m/z 363(M-H)-

후처리

  1. customIt was purified by dilution with methylene chloride and precipitation with hexane
  2. filtrationFiltering

출처 및 근거

ORD 기록
ord-52f3d2e43f15457aa4dd245037d233e3
출처 데이터셋
uspto-grants-1998_07
특허 번호
US05780483

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