1H-Imidazole-1-propanal → N-[1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamine

HRID 1956887노트

반응식

HRID 1956887 반응식
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([NH2:24])([CH3:23])[CH3:22])=[CH:17][CH:16]=2)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:25]1([CH2:30][CH2:31][CH:32]=O)[CH:29]=[CH:28][N:27]=[CH:26]1>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:16]=[CH:17][C:18]([C:21]([NH:24][CH2:32][CH2:31][CH2:30][N:25]3[CH:29]=[CH:28][N:27]=[CH:26]3)([CH3:22])[CH3:23])=[CH:19][CH:20]=2)=[CH:11][CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 47122741H-Imidazole-1-propanalHCID 183496501-(4'-Benzyloxybiphenyl-4-yl)-1-methylethylamine

생성물 1

HCID 18349622N-[1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamine

실험 절차

In a similar manner to Example 24, 1-(4'-benzyloxybiphenyl-4-yl)-1-methylethylamine (Al5) (1.4 g) and 3-(imidazol-1-yl)propionaldehyde (0.72 g) were reacted to give N-[1-(4'-benzyloxybiphenyl-4-yl)-1-methylethyl)-3-(imidazol-1-yl)propylamine, m.p. 93°-95° C.

출처 및 근거

ORD 기록
ord-1b15368b24554ce4adaa624b7a0970c1
출처 데이터셋
uspto-grants-1998_07
특허 번호
US05780642

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