Pyridinium → HCID 19069252, 화합물
반응식
[CH:1]1([O:7][C:8]2[CH:15]=[CH:14][C:11]([CH2:12][OH:13])=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH:1]1([O:7][C:8]2[CH:9]=[CH:10][C:11]([CH:12]=[O:13])=[CH:14][CH:15]=2)[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1참가 물질
4
실험 절차
The alcohol prepared above (4.24 g, 20.7 mmol) was dissolved in 250 mL methylene chloride under an atmosphere of dry nitrogen. Pyridinium chlorochormate (5.62 g, 26.1 mmol) was added over 5 minutes. After stirring at ambient temperature for 72 hours, the mixture was filtered through Celite and concentrated in vacuo. Flash silica gel chromatography eluting with 10% ethyl acetate in hexane afforded 3.25 g (77%) of the title compound.
후처리
- filtrationthe mixture was filtered through Celite
- concentrationconcentrated in vacuo
- washFlash silica gel chromatography eluting with 10% ethyl acetate in hexane
출처 및 근거
- ORD 기록
- ord-8fd926940899474bbd0f19a5fede7ff9
- 출처 데이터셋
- uspto-grants-1998_07
- 특허 번호
- US05783593
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