Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → (+/-)-1-(Cyclohexylmethyl)-4-(oxiran-2-ylmethyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate | HCID 286836 | — |
| 반응물 | 1-(Cyclohexylmethyl)piperazine | HCID 2735885 | — |
| 생성물 | (+/-)-1-(Cyclohexylmethyl)-4-(oxiran-2-ylmethyl)piperazine | HCID 86661984 | 92% |
반응 단계
The same method as employed in the preparation of Intermediate 1 but starting from 1-cyclohexylmethyl piperazine and (±)-3-nitro-benzenesulfonic acid oxiranylmethyl ester gives after flash chromatography the title compound as a yellow oil in a 92% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08410110B2 |
| 출처 데이터셋 | uspto-grants-2013_04 |
| ORD ID | ord-2536eeedebbf49a0b6412589d7783b57 |
| 출처 메모 | uspto-grants-2013_04 |