Trifluoroacetic acid → 2-(3-Bromo-5-chloro-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid ethyl ester

반응식

[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[cH:17][c:18]([Br:23])[cH:19][c:20]([Cl:22])[cH:21]1)[C:10]([CH3:24])([CH3:25])[CH:9]2[OH:26].[CH2:34]([SiH:35]([CH2:36][CH3:37])[CH2:38][CH3:39])[CH3:40].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[cH:17][c:18]([Br:23])[cH:19][c:20]([Cl:22])[cH:21]1)[C:10]([CH3:24])([CH3:25])[CH2:9]2

참가 물질

반응물 3

HCID 6422Trifluoroacetic acid

HCID 12052Triethylsilane

HCID 674422802-(3-Bromo-5-chloro-phenyl)-4-hydroxy-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid ethyl ester

생성물 1

HCID 674409902-(3-Bromo-5-chloro-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid ethyl ester

출처 및 근거

ORD 기록: ord-a2da9cd851fa4e999759991851686e01
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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