5-(azetidin-1-ylcarbonyl)-N-(tert-butyl)furan-2-sulfonamide → 5-(Azetidin-1-ylcarbonyl)furan-2-sulfonamide
반응식
[N:1]1([C:5]([C:7]2[O:11][C:10]([S:12]([NH:15]C(C)(C)C)(=[O:14])=[O:13])=[CH:9][CH:8]=2)=[O:6])[CH2:4][CH2:3][CH2:2]1>FC(F)(F)C(O)=O>[N:1]1([C:5]([C:7]2[O:11][C:10]([S:12]([NH2:15])(=[O:14])=[O:13])=[CH:9][CH:8]=2)=[O:6])[CH2:4][CH2:3][CH2:2]1참가 물질
3
실험 절차
A solution of 5-(azetidin-1-ylcarbonyl)-N-(tert-butyl)furan-2-sulfonamide (the product of step ii) (3 g) in trifluoroacetic acid (90 mL) was stirred at room temperature. After 18 h the mixture was evaporated to dryness in vacuo. The resulting oil was triturated with Et2O and filtered to give the subtitle compound as a white solid. Yield: 1.75 g.
후처리
- customAfter 18 h the mixture was evaporated to dryness in vacuo
- customThe resulting oil was triturated with Et2O
- filtrationfiltered
출처 및 근거
- ORD 기록
- ord-d41bc571ec204712a729cf7427345a1d
- 출처 데이터셋
- uspto-grants-2013_04
- 특허 번호
- US08410123B2
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