Sulfamide → 4-Pyrimidin-2-ylpiperazine-1-sulfonamide

HRID 1958982노트

반응식

HRID 1958982 반응식
[N:1]1([C:7]2[N:12]=[CH:11][CH:10]=[CH:9][N:8]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[S:13](N)([NH2:16])(=[O:15])=[O:14]>O1CCOCC1>[N:12]1[CH:11]=[CH:10][CH:9]=[N:8][C:7]=1[N:1]1[CH2:6][CH2:5][N:4]([S:13]([NH2:16])(=[O:15])=[O:14])[CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 82267SulfamideHCID 887471-(2-Pyrimidinyl)piperazine

생성물 1

HCID 115722974-Pyrimidin-2-ylpiperazine-1-sulfonamide

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

The subtitle compound was prepared according to the procedure outlined in example 15 step i) using 2-piperazin-1-ylpyrimidine (3.0 g) and sulfamide (1.2 g) in dioxane (30 mL) to give the subtitle compound as a white solid. Yield: 2.06 g.

후처리

  1. customThe subtitle compound was prepared

출처 및 근거

ORD 기록
ord-a9ba52fb76e94d6f9380ae6285712004
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08410123B2

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