1,4-Dioxane hydrochloride → HCID 59442938, 화합물

HRID 1959138노트

반응식

HRID 1959138 반응식
[C:1]([C:4]1[C:5]([CH3:30])([CH3:29])[O:6][C:7]2[C:12]([C:13]=1[C:14]1[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=1)=[CH:11][CH:10]=[C:9]([NH:21]C(=O)OC(C)(C)C)[CH:8]=2)(=[O:3])[CH3:2].Cl.O1CCOCC1>>[NH2:21][C:9]1[CH:8]=[C:7]2[C:12]([C:13]([C:14]3[CH:15]=[CH:16][C:17]([F:20])=[CH:18][CH:19]=3)=[C:4]([C:1](=[O:3])[CH3:2])[C:5]([CH3:30])([CH3:29])[O:6]2)=[CH:11][CH:10]=1

참가 물질

3

반응물 2

HCID 204431481,4-Dioxane hydrochlorideHCID 59442967HCID 59442967, 화합물

생성물 1

HCID 59442938HCID 59442938, 화합물

실험 절차

The compound obtained in (3) described above (147 mg) and 4N hydrochloric acid-dioxane solution (4 mL) were treated in the same manner as Reference Example 5(5) to give the titled compound as a crude product.

출처 및 근거

ORD 기록
ord-cb322130be0648b2b68da29d5ad51617
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08410166B2

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