(3,5-Dichloropyridin-4-yl)methanol → [5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-yl]-methanol

HRID 1959566노트

반응식

HRID 1959566 반응식
ClC1C=NC=C(Cl)C=1CO.[Cl:11][C:12]1[C:13]([CH2:20][O:21][CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][O:23]2)=[C:14]([CH:18]=[O:19])[CH:15]=[N:16][CH:17]=1>>[Cl:11][C:12]1[C:13]([CH2:20][O:21][CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][O:23]2)=[C:14]([CH2:18][OH:19])[CH:15]=[N:16][CH:17]=1

참가 물질

3

반응물 2

HCID 17855219(3,5-Dichloropyridin-4-yl)methanolHCID 441904745-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine-3-carbaldehyde

생성물 1

HCID 44190475[5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-yl]-methanol

실험 절차

Reduction of the aldehyde group in 5-chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridine-3-carbaldehyde according to the synthesis of (3,5-dichloro-pyridin-4-yl)-methanol yielded the title compound. MS (m/z): 258.2 [M+H+].

출처 및 근거

ORD 기록
ord-753a16db67ed42cd813d66342f9f3e09
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08410134B2

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