Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Formylphenylboric acid → 2-(Trimethylsilyl)ethyl 4-(4-formylphenyl)isoquinoline-6-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Formylphenylboric acid | HCID 21940015 | — |
| 반응물 | 2-(Trimethylsilyl)ethyl 4-{[(trifluoromethyl)sulfonyl]oxy}isoquinoline-6-carboxylate | HCID 58495760 | — |
| 생성물 | 2-(Trimethylsilyl)ethyl 4-(4-formylphenyl)isoquinoline-6-carboxylate | HCID 86661966 | 79.7% |
반응 단계
Using 2-(trimethylsilyl)ethyl 4-{[(trifluoromethyl)sulfonyl]oxy}isoquinoline-6-carboxylate (600 mg, 1.42 mmol) and 4-formylphenylboric acid (320 mg, 2.14 mmol), the desired title compound (427 mg, yield 79%) was obtained by the same method as in Example 8 (8a).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08410273B2 |
| 출처 데이터셋 | uspto-grants-2013_04 |
| ORD ID | ord-0fadfcfdb6754866851a45ba02dd125c |
| 출처 메모 | uspto-grants-2013_04 |