4-(4-Bromobenzoyl)morpholine → 3-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carboxamide

HRID 1961504

반응식

HRID 1961504 반응식
[NH2:1][C:2]1[C:6]([C:7]([NH2:9])=[O:8])=[CH:5][N:4]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:3]=1.Br[C:17]1[CH:30]=[CH:29][C:20]([C:21]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[O:22])=[CH:19][CH:18]=1>>[N:23]1([C:21]([C:20]2[CH:19]=[CH:18][C:17]([NH:1][C:2]3[C:6]([C:7]([NH2:9])=[O:8])=[CH:5][N:4]([C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=4)[N:3]=3)=[CH:30][CH:29]=2)=[O:22])[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1

참가 물질

3

반응물 2

HCID 5321484-(4-Bromobenzoyl)morpholineHCID 88319093-amino-1-phenyl-1H-pyrazole-4-carboxamide

생성물 1

HCID 446262703-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carboxamide

실험 절차

3-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-1-phenyl-1H-pyrazole-4-carboxamide was prepared according to the general procedure in Example 1 Step 4 using 3-amino-1-phenyl-1H-pyrazole-4-carboxamide (52 mg, 0.257 mmol) and 4-(4-bromobenzoyl)morpholine (69.5 mg, 0.257 mmol) as the starting materials.

출처 및 근거

ORD 기록
ord-24b7b074d6f6432d9f5fb4370e6e28c0
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08415346B2

연결된 노트

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