(4-Chloro-phenyl)-(6-chloro-pyrazin-2-yl)-carbamic acid tert-butyl ester → (4-Chloro-phenyl)-[6-(6-methoxy-pyridin-2-yl)-pyrazin-2-yl]-carbamic acid tert-butyl ester

HRID 1961705노트

반응식

HRID 1961705 반응식
[C:1]([O:5][C:6](=[O:22])[N:7]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)[C:8]1[CH:13]=[N:12][CH:11]=[C:10](Cl)[N:9]=1)([CH3:4])([CH3:3])[CH3:2].[Br-].[CH3:24][O:25][C:26]1[N:31]=[C:30]([Zn+])[CH:29]=[CH:28][CH:27]=1>>[C:1]([O:5][C:6](=[O:22])[N:7]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)[C:8]1[CH:13]=[N:12][CH:11]=[C:10]([C:30]2[CH:29]=[CH:28][CH:27]=[C:26]([O:25][CH3:24])[N:31]=2)[N:9]=1)([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 59570677(4-Chloro-phenyl)-(6-chloro-pyrazin-2-yl)-carbamic acid tert-butyl esterHCID 178491785HCID 178491785, 화합물

생성물 1

HCID 59570669(4-Chloro-phenyl)-[6-(6-methoxy-pyridin-2-yl)-pyrazin-2-yl]-carbamic acid tert-butyl ester

실험 절차

Was prepared according to Example 5 from (4-chloro-phenyl)-(6-chloro-pyrazin-2-yl)-carbamic acid tert-butyl ester and 6-methoxy-2-pyridylzinc bromide.

후처리

  1. customWas prepared

출처 및 근거

ORD 기록
ord-6475b6ad910b474da805d9c83c6731eb
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08415358B2

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