5-Bromo-3-fluoro-2-methylaniline → (5-Bromo-3-fluoro-2-methyl-phenyl)-acetic acid
반응식
[Br:1][C:2]1[C:3](F)=[CH:4][C:5]([CH3:12])=[C:6]([CH2:8][C:9]([OH:11])=[O:10])[CH:7]=1.BrC1C=C([F:23])C(C)=C(N)C=1>>[Br:1][C:2]1[CH:3]=[C:4]([F:23])[C:5]([CH3:12])=[C:6]([CH2:8][C:9]([OH:11])=[O:10])[CH:7]=1참가 물질
3
실험 절차
(5-Bromo-3-fluoro-2-methyl-phenyl)-acetic acid was prepared analogously to the synthesis of (5-bromo-4-fluoro-2-methyl-phenyl)-acetic acid (preparation example P5, step P5.3) starting from 5-bromo-3-fluoro-2-methyl-phenylamine (preparation example P7, step P7.1) by making use of the procedures described under step P5.1, step P5.2 and step P5.3. The title acid was obtained as a solid, mp: 147° C.
출처 및 근거
- ORD 기록
- ord-3cf5c538ee0f48f39629e0148c3f5e9f
- 출처 데이터셋
- uspto-grants-2013_04
- 특허 번호
- US08415369B2
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