Acetic Acid → HCID 67239262, 화합물

HRID 1963680노트

반응식

HRID 1963680 반응식
C(O[C:9]1[CH:14]=[C:13]([S:15]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=2)(=[O:17])=[O:16])[C:12]([F:26])=[CH:11][C:10]=1[C:27]1[CH:32]=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=1)C1C=CC=CC=1.[H][H].C(O)(=[O:38])C>[Pd]>[F:26][C:12]1[CH:11]=[C:10]([C:27]2[C:32]([OH:38])=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=2)[CH:9]=[CH:14][C:13]=1[S:15]([C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)(=[O:16])=[O:17]

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 68089499HCID 68089499, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 67239262HCID 67239262, 화합물

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

A suspension of the product of step (ii) (838 mg) in acetic acid (30 ml) and 10% Pd/C (200 mg) was stirred under 2 bar pressure of hydrogen for 30 min. The catalyst was removed by filtration and the filtrate was evaporated to give the subtitle compound, yield 630 mg.

후처리

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated

출처 및 근거

ORD 기록
ord-9d80e81b84a043689c79567b3e3b7abd
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08415394B2

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