2-(Pyridin-4-yl)aniline → HCID 44250947, 화합물
반응식
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH2:13])=[CH:3][CH:2]=1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([NH:21][C:22](=[O:29])[CH2:23][O:24][CH2:25][C:26](O)=[O:27])=[C:17]([C:30]([O:32]C)=[O:31])[CH:16]=1>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([NH:21][C:22](=[O:29])[CH2:23][O:24][CH2:25][C:26](=[O:27])[NH:13][C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[C:4]2[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=2)=[C:17]([CH:16]=1)[C:30]([OH:32])=[O:31]참가 물질
3
실험 절차
Using the same method as in Example 1-(ii), 2-pyridin-4-yl-phenylamine was reacted with the (2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethoxy)acetic acid obtained in Example 1-(i) to give 5-chloro-2-([(2-oxo-2-([2-(pyridin-4-yl)phenyl]amino)ethoxy)acetyl]amino)benzoic acid.methyl ester (yield: 22%).
출처 및 근거
- ORD 기록
- ord-758dea02821d40829555d30dec7cd5aa
- 출처 데이터셋
- uspto-grants-2013_04
- 특허 번호
- US08415479B2