1,1-Dimethylethyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate → Tert-butyl 1-[5-[(3,5-difluorophenyl)carbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylate

HRID 196439

반응식

HRID 196439 반응식
[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12]([F:17])[cH:13][c:14]([F:16])[cH:15]2)[cH:18]1.[NH:19]1[CH:20]2[CH:21]([CH2:22][CH2:23]1)[CH2:24][N:25]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:26]2>>[c:2]1([N:19]2[CH:20]3[CH:21]([CH2:22][CH2:23]2)[CH2:24][N:25]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:26]3)[cH:3][n:4][cH:5][c:6]([C:7](=[O:8])[NH:9][c:10]2[cH:11][c:12]([F:17])[cH:13][c:14]([F:16])[cH:15]2)[cH:18]1

참가 물질

3

반응물 2

HCID 225622051,1-Dimethylethyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylateHCID 416011495-bromo-N-(3,5-difluorophenyl)nicotinamide

생성물 1

HCID 67265700Tert-butyl 1-[5-[(3,5-difluorophenyl)carbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylate

출처 및 근거

ORD 기록
ord-f98077fe217647229aff89db12db3f38
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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