Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzylamine → N-benzyl-3-[(4-tert-butylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzylamine | HCID 7504 | — |
| 반응물 | 4-t-Butylbenzenesulfonyl chloride | HCID 139882 | — |
| 반응물 | 3-(tert-Butoxycarbonyl)-1,3-thiazolidine-2-carboxylic acid | HCID 4644094 | — |
| 반응물 | Benzophenone, 4-nitro-, oxime | HCID 6506582 | — |
| 생성물 | N-benzyl-3-[(4-tert-butylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxamide | HCID 11339104 | — |
반응 단계
Following the general solid phase method as outlined Example 33, starting from 3-(tert-butoxycarbonyl)-1,3-thiazolidine-2-carboxylic acid, Kaiser oxime resin, 4-tert-butylbenzenesulfonyl chloride and benzylamine, the title compound was obtained in 97.1% purity by HPLC.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08415480B2 |
| 출처 데이터셋 | uspto-grants-2013_04 |
| ORD ID | ord-9c8311136e4b4fc89c2db75a6c57dc15 |
| 출처 메모 | uspto-grants-2013_04 |