Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzhydrylamine → N-benzhydryl-3-([1,1'-biphenyl]-4-ylsulfonyl)-1,3-thiazolidine-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzhydrylamine | HCID 7036 | — |
| 반응물 | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
| 반응물 | 3-(tert-Butoxycarbonyl)-1,3-thiazolidine-2-carboxylic acid | HCID 4644094 | — |
| 반응물 | Benzophenone, 4-nitro-, oxime | HCID 6506582 | — |
| 생성물 | N-benzhydryl-3-([1,1'-biphenyl]-4-ylsulfonyl)-1,3-thiazolidine-2-carboxamide | HCID 10311490 | — |
반응 단계
Following the general solid phase method as outlined Example 33, starting from 3-(tert-butoxy-carbonyl)-1,3-thiazolidine-2-carboxylic acid, Kaiser oxime resin, 1,1′-biphenyl-4-sulfonyl chloride and benzhydrylamine, the title compound was obtained in 98.5% purity by HPLC.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08415480B2 |
| 출처 데이터셋 | uspto-grants-2013_04 |
| ORD ID | ord-ad7fb46b62bd432a96d0fea982e55e96 |
| 출처 메모 | uspto-grants-2013_04 |