HCID 67356276, 화합물 → HCID 67356531, 화합물
반응식
O[C:2]1([C:23]2[C:32]([OH:33])=[CH:31][C:26]3[O:27][CH2:28][CH2:29][O:30][C:25]=3[CH:24]=2)[C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][C:9]=2[O:11][CH3:12])[N:4]([CH2:15][CH2:16][O:17][CH2:18][CH2:19][O:20][CH3:21])[C:3]1=[O:22].ClC1C=CC=C2C=1C(O)(C1C(O)=CC3OCCC=3C=1)C(=O)N2C(C1C=CC=CC=1)C1C=CC=CC=1>>[OH:33][C:32]1[C:23]([CH:2]2[C:10]3[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][C:9]=3[O:11][CH3:12])[N:4]([CH2:15][CH2:16][O:17][CH2:18][CH2:19][O:20][CH3:21])[C:3]2=[O:22])=[CH:24][C:25]2[O:30][CH2:29][CH2:28][O:27][C:26]=2[CH:31]=1참가 물질
3
실험 절차
Following the procedure as described in PREPARATION 4C, and making non-critical variations using 3-hydroxy-3-(7-hydroxy-2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dimethoxy-1-[2-(2-methoxyethoxy)ethyl]-1,3-dihydro-2H-indol-2-one to replace 4-chloro-1-(diphenylmethyl)-3-hydroxy-3-(6-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-1,3-dihydro-2H-indol-2-one, 3-(7-hydroxy-2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dimethoxy-1-[2-(2-methoxyethoxy)ethyl]-1,3-dihydro-2H-indol-2-one was obtained (89%) as a yellow solid: MS (ES+) m/z 446.0 (M+1).
출처 및 근거
- ORD 기록
- ord-803b323b25a04445b7393c56aaffe821