4-Chloro-8-methoxy-2-methylquinoline → [(R)-1-(4-Chlorophenyl)-ethyl]-(8-methoxy-2-methylquinolin-4-yl)-amine

HRID 1966536

반응식

HRID 1966536 반응식
Cl[C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1.[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C@H:22]([NH2:24])[CH3:23])=[CH:18][CH:17]=1>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C@H:22]([NH:24][C:2]2[C:11]3[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=3)[N:5]=[C:4]([CH3:14])[CH:3]=2)[CH3:23])=[CH:18][CH:17]=1

참가 물질

3

반응물 2

HCID 8075834-Chloro-8-methoxy-2-methylquinolineHCID 1715226(1R)-1-(4-chlorophenyl)ethan-1-amine

생성물 1

HCID 59474735[(R)-1-(4-Chlorophenyl)-ethyl]-(8-methoxy-2-methylquinolin-4-yl)-amine

실험 절차

Preparation was made using a similar procedure as described in example 41. Starting materials were 4-chloro-8-methoxy-2-methylquinoline and (R)-1-(4-chloro-phenyl)ethylamine.

후처리

  1. customPreparation

출처 및 근거

ORD 기록
ord-aeb8feb8a9254691bd826e287421f688
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08420670B2

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