2-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane → 5,8-Dioxaspiro[3.4]octane-2-methanol

HRID 1966814노트

반응식

HRID 1966814 반응식
C([O:8][CH2:9][CH:10]1[CH2:13][C:12]2([O:17][CH2:16][CH2:15][O:14]2)[CH2:11]1)C1C=CC=CC=1>CO.[Pd]>[CH2:11]1[C:12]2([O:17][CH2:16][CH2:15][O:14]2)[CH2:13][CH:10]1[CH2:9][OH:8]

참가 물질

4

반응물 1

HCID 120735822-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane

생성물 1

HCID 120735835,8-Dioxaspiro[3.4]octane-2-methanol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

Palladium/carbon (10%) was added to a solution of 2-[(benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane (22.0 gm, 94.0 mmol) (step c) in methanol and the mixture was stirred at room temperature under hydrogen balloon for about 4 hours. It was filtered through celite bed and residue was washed with methanol. The combined filtrate was concentrated under reduced pressure.

후처리

  1. filtrationIt was filtered through celite bed and residue
  2. washwas washed with methanol
  3. concentrationThe combined filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-7de2674c31184f9e89e447183164d3c9
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08420666B2

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