4-{[(Benzyloxy)carbonyl]amino}-5-methoxy-2,2-dimethyl-3-oxopentanoate → HCID 59556989, 화합물
반응식
C(OC([NH:11][CH:12]([CH2:21][O:22][CH3:23])[C:13](=[O:20])[C:14]([CH3:19])([CH3:18])[C:15]([O-])=[O:16])=O)C1C=CC=CC=1>CO.[C].[Pd]>[CH3:23][O:22][CH2:21][CH:12]1[NH:11][C:15](=[O:16])[C:14]([CH3:19])([CH3:18])[C:13]1=[O:20]참가 물질
4
실험 절차
To a solution of 4-{[(benzyloxy)carbonyl]amino}-5-methoxy-2,2-dimethyl-3-oxopentanoate (10.2 g) in methanol (100 mL) was added 10% palladium carbon (containing 50% water, 3.1 g), and the mixture was stirred overnight under a hydrogen atmosphere. Palladium carbon was filtered off, and the filtrate was concentrated under reduced pressure. The obtained solid was washed with hexane to give the title compound as colorless crystals (yield: 4.16 g, 84%).
후처리
- filtrationPalladium carbon was filtered off
- concentrationthe filtrate was concentrated under reduced pressure
- washThe obtained solid was washed with hexane
출처 및 근거
- ORD 기록
- ord-e1a865582e4a45029bce5321d6fdf2aa
- 출처 데이터셋
- uspto-grants-2013_04
- 특허 번호
- US08420694B2
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