Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1968407생성일: 2026년 10월 24일
Ethyl Acetate → (E)-2-(acetoxy-methyl)-6-(4-(3,5-dimethoxystyryl)phenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate
https://huagongshe.com/ko/reaction/1968407
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | alpha-D-Glucopyranosyl bromide, tetraacetate | HCID 101776 | — |
| 반응물 | Pterostilbene | HCID 5281727 | — |
| 촉매 | Benzyltriethylammonium bromide | HCID 165294 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | (E)-2-(acetoxy-methyl)-6-(4-(3,5-dimethoxystyryl)phenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate | HCID 69198447 | — |
반응 단계
To a solution of acetobromo-α-D-glucose (48 mg, 0.11 mM) and benzyltriethylammonium bromide (13 mg, 0.04 mM) in chloroform was added a solution of pterostilbene (30 mg, 0.11 mM)) in 1.25 M (2.5 mL) of NaOH. The mixture was stirred at 60° C. for 5 h and after a second addition of 10 mg of acetobromo-α-D-glucose and 1.0 mL of NaOH) the mixture was stirred at 60° C. for additional 5 h. Ethyl acetate was added and the organic phase was washed with water. The crude mixture was purified using flash chromatography eluting with ethyl acetate/hexanes (3:2) and afforded (E)-2-(acetoxy-methyl)-6-(4-(3,5-dimethoxystyryl)phenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08426369B2 |
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| 출처 데이터셋 | uspto-grants-2013_04 |
|---|
| ORD ID | ord-1b30e9048f834828bdeaaab8034badb9 |
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| 출처 메모 | uspto-grants-2013_04 |
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