Ethylamine → [3-(4-Bromo-2-ethylaminomethyl-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester

HRID 1969032노트

반응식

HRID 1969032 반응식
[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([O:13][C:14]2[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][C:15]=2[CH:21]=O)[CH:6]=1.[CH2:24]([NH2:26])[CH3:25]>>[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([O:13][C:14]2[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][C:15]=2[CH2:21][NH:26][CH2:24][CH3:25])[CH:6]=1

참가 물질

3

반응물 2

HCID 6341EthylamineHCID 58237628[3-(4-Bromo-2-formyl-phenoxy)-4-methoxy-phenyl]acetic acid methyl ester

생성물 1

HCID 58288534[3-(4-Bromo-2-ethylaminomethyl-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester

실험 절차

Prepared according to the procedure described in Example 3, Step 2, using the following starting materials: [3-(4-bromo-2-formyl-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester and ethylamine (2M in THF).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-d379fe9223194ddc95c652eea44d3773
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08426449B2

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