Acetyl chloride → (3-{2-[(Acetyl-benzyl-amino)-methyl]-4-bromo-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester

HRID 1969035노트

반응식

HRID 1969035 반응식
[CH2:1]([O:3][C:4](=[O:31])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH2:22][NH:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:7]=1)[CH3:2].[C:32](Cl)(=[O:34])[CH3:33]>>[CH2:1]([O:3][C:4](=[O:31])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH2:22][N:23]([C:32](=[O:34])[CH3:33])[CH2:24][C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH:7]=1)[CH3:2]

참가 물질

3

반응물 2

HCID 6367Acetyl chlorideHCID 58288503HCID 58288503, 화합물

생성물 1

HCID 58288497(3-{2-[(Acetyl-benzyl-amino)-methyl]-4-bromo-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester

실험 절차

Prepared according to the procedure described in Example 3, Step 3, using the following starting materials: {3-[2-(benzylamino-methyl)-4-bromo-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester and acetyl chloride.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-e19a30d610c147d4b128c31e1d2a42ca
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08426449B2

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