Methyl chloroformate → (3-{2-[(Indan-2-yl-methoxycarbonyl-amino)-methyl]-4-trifluoromethyl-phenoxy}-phenyl)-acetic acid methyl ester

HRID 1969057노트

반응식

HRID 1969057 반응식
[CH3:1][O:2][C:3](=[O:33])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:13]=2[CH2:22][NH:23][CH:24]2[CH2:32][C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[CH2:25]2)[CH:6]=1.Cl[C:35]([O:37][CH3:38])=[O:36]>>[CH3:1][O:2][C:3](=[O:33])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:19])[F:20])=[CH:14][C:13]=2[CH2:22][N:23]([CH:24]2[CH2:32][C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[CH2:25]2)[C:35]([O:37][CH3:38])=[O:36])[CH:6]=1

참가 물질

3

반응물 2

HCID 6586Methyl chloroformateHCID 58288478{3-[2-(Indan-2-ylaminomethyl)-4-trifluoromethyl-phenoxy]-phenyl}-acetic acid methyl ester

생성물 1

HCID 58288508(3-{2-[(Indan-2-yl-methoxycarbonyl-amino)-methyl]-4-trifluoromethyl-phenoxy}-phenyl)-acetic acid methyl ester

실험 절차

Prepared according to the procedure described in Example 3, Step 3, using the following starting materials: {3-[2-(indan-2-ylaminomethyl)-4-trifluoromethyl-phenoxy]-phenyl}-acetic acid methyl ester and methyl chloroformate.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-d15ebdfc25ca4ec2a72b7d34d18a598c
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08426449B2

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