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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1970186생성일: 2026년 10월 27일

Potassium Carbonate → 4-Methylamino-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

https://huagongshe.com/reaction/1970186

반응식

참여 물질

역할이름HCID투입량
반응물Potassium CarbonateHCID 11430—
반응물4-[Methyl-(2,2,2-trifluoro-acetyl)-amino]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl esterHCID 87365907—
용매MethanolHCID 887—
생성물4-Methylamino-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl esterHCID 53414200—

반응 단계

To a solution of 4-[Methyl-(2,2,2-trifluoro-acetyl)-amino]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester (0.26 g, 0.73 mmol) in methanol (3 mL) was added an aqueous 1.0M solution of potassium carbonate. The reaction mixture was stirred at room temperature for 5 hours and the solvent evaporated in vacuo to yield the title compound which was used directly without further purification.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08426604B2
출처 데이터셋uspto-grants-2013_04
ORD IDord-71434d124111415ebe4d11ce6267f3f5
출처 메모uspto-grants-2013_04