Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 3-phenylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 3-Phenylbutyric acid | HCID 20724 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | Methyl 3-phenylbutanoate | HCID 137945 | — |
반응 단계
Thionyl chloride (44 ml, 91.4 mmol) is added dropwise to methanol (30 ml) at 0° C., followed by 3-phenylbutyric acid (10 g, 60.9 mmol). The reaction is stirred for 4 hours and the solvent is evaporated. The residue is partitioned between t-butylnethyl ether and aqueous ammonia. The organic phase is washed with water and brine, dried (Na2SO4) and evaporated to afford the title compound. MH+179.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745462B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-dabb0134a3664218ab80ff869d75d7fc |
| 출처 메모 | uspto-grants-2010_06 |