Acetonitrile → 1,1,1-trifluoro-2-(4-((2S)-2-(2-oxa-6-azaspiro[3.3]hept-6-ylmethyl)-4-(2-thiophenylsulfonyl)-1-piperazinyl)phenyl)-2-propanol

반응식

CS(O[CH2:6][C@H:7]1[CH2:12][N:11]([S:13]([C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)(=[O:15])=[O:14])[CH2:10][CH2:9][N:8]1[C:21]1[CH:26]=[CH:25][C:24]([C:27]([OH:33])([CH3:32])[C:28]([F:31])([F:30])[F:29])=[CH:23][CH:22]=1)(=O)=O.[CH2:34]1[C:37]2([CH2:40][NH:39][CH2:38]2)[CH2:36][O:35]1.C(=O)([O-])[O-].[K+].[K+].CC#N>C(Cl)Cl>[F:31][C:28]([F:29])([F:30])[C:27]([C:24]1[CH:23]=[CH:22][C:21]([N:8]2[CH2:9][CH2:10][N:11]([S:13]([C:16]3[S:17][CH:18]=[CH:19][CH:20]=3)(=[O:14])=[O:15])[CH2:12][C@@H:7]2[CH2:6][N:39]2[CH2:40][C:37]3([CH2:36][O:35][CH2:34]3)[CH2:38]2)=[CH:26][CH:25]=1)([OH:33])[CH3:32]