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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 19726생성일: 2026년 10월 24일

Phthalic Anhydride → 2-(2-Hydroxymethylindan-2-yl)-isoindole-1,3-dione

https://huagongshe.com/ko/reaction/19726

반응식

참여 물질

역할이름HCID투입량
반응물Phthalic AnhydrideHCID 6811—
반응물(2-Amino-2,3-dihydro-1H-inden-2-yl)methanolHCID 22080542—
용매WaterHCID 962—
생성물2-(2-Hydroxymethylindan-2-yl)-isoindole-1,3-dioneHCID 68561206—

반응 조건

온도160 °C

반응 단계

A mixture of (2-aminoindan-2-yl)methanol (0.407 g, 2.50 mmol) and phthalic anhydride (0.369 g, 2.50 mmol) is heated at 160° C. for 40 minutes. The reaction mixture is poured into water and extracted with chloroform. The organic phase is dried (Na2SO4) and evaporated to afford 2-(2-hydroxymethylindan-2-yl)-isoindole-1,3-dione, MH+294.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07745462B2
출처 데이터셋uspto-grants-2010_06
ORD IDord-9c2a51c334da45ef9b380da3998da7ac
출처 메모uspto-grants-2010_06