Acetic Acid → Carbendazim

HRID 1973427

반응식

HRID 1973427 반응식
[C:1]([NH:3][C:4](=[O:7])[O:5][CH3:6])#[N:2].[C:8]1(N)[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH2:14].C(O)(=O)C>O>[N:2]1[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[NH:14][C:1]=1[NH:3][C:4]([O:5][CH3:6])=[O:7]

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 7243O-PhenylenediamineHCID 89023Methyl N-cyanocarbamate

생성물 1

HCID 25429Carbendazim수율 72%

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
50 °C

실험 절차

A solution of 5.0 parts of the salt of methyl cyanocarbamate with o-phenylenediamine and 1.5 parts of acetic acid in 25 parts of water is refluxed for 30 minutes. The solution is cooled to 50° C. and filtered. The product is washed with water and dried in vacuo at 95° C. This procedure gives 3.3 parts (72% yield) of 2-benzimidazolecarbamic acid, methyl ester.

후처리

  1. filtrationfiltered
  2. washThe product is washed with water
  3. customdried in vacuo at 95° C

출처 및 근거

ORD 기록
ord-3da346668bc146ccb8ddc4a1ee5b499a
출처 데이터셋
uspto-grants-1976_12
특허 번호
US03997553

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