Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzaldehyde → (S)-3-tert. butyl-5-hydroxy-methyl-2-phenyloxazolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzaldehyde | HCID 240 | — |
| 반응물 | Benzene | HCID 241 | — |
| 반응물 | (S)-3-(tert-Butylamino)propane-1,2-diol | HCID 2733671 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | (S)-3-tert. butyl-5-hydroxy-methyl-2-phenyloxazolidine | HCID 86734277 | — |
반응 단계
22 g of (S)-1-tert.butylamino-2,3-dihydroxypropane, 20.7 g of benzaldehyde and 46 cc of benzene are heated at reflux in a water separator for 16 hours. The benzene and benzaldehyde are removed by distillation and the residue is distilled in a high vacuum. (S)-3-tert. butyl-5-hydroxy-methyl-2-phenyloxazolidine is obtained as yellowish oil (B.P. 110°-125° at 0.01 mm of Hg); [α]20546 = 17.8° (c = 1.99; chloroform).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03998835 |
| 출처 데이터셋 | uspto-grants-1976_12 |
| ORD ID | ord-87237c1e6f21415095e22b72680f230e |
| 출처 메모 | uspto-grants-1976_12 |