Hydrazine → 4-(Benzyloxy)-3-chlorobenzohydrazide
반응식
[CH2:1]([O:8][C:9]1[CH:19]=[CH:18][C:12]([C:13](OCC)=[O:14])=[CH:11][C:10]=1[Cl:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:21][NH2:22]>CO>[CH2:1]([O:8][C:9]1[CH:19]=[CH:18][C:12]([C:13]([NH:21][NH2:22])=[O:14])=[CH:11][C:10]=1[Cl:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1참가 물질
4
실험 절차
Ethyl 4-benzyloxy-3-chlorobenzoate [c.f., Jones & Robinson, J. Chem. Soc. 3845 (1955)] (32.0 g., 0.11 mole), 25 ml. methanol and 20 ml. 95% hydrazine are stirred under reflux for 8 hours and cooled to room temperature. The mixture is filtered and the resulting solid dried in vacuo to give 29.4 g. 4-benzyloxy- 3-chlorobenzoic acid hydrazide (96.7% yield), m.p. 168°-171° C.
후처리
- temperatureunder reflux for 8 hours
- filtrationThe mixture is filtered
- customthe resulting solid dried in vacuo
- customto give 29.4 g
출처 및 근거
- ORD 기록
- ord-18ab156da6274b98990f5c5ca8db38a5
- 출처 데이터셋
- uspto-grants-1976_12
- 특허 번호
- US03998958
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