참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-Methoxy-4-nitropyridine-n-oxide | HCID 579207 | — |
| 촉매 | Iron | HCID 23925 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-Methoxypyridin-4-amine | HCID 280891 | — |
반응 단계
A mixture of 6.3 g of 2-methoxy-4-nitropyridine N-oxide and 12.6 g of iron powder in 150 ml of acetic acid is heated for 1 hour at 100° C. After cooling, sodium hydroxide is added, the mixture is then filtered and the material on the filter is washed with water. The aqueous phase is extracted with ethyl ether. After drying and concentration, 3.6 g of an oil are recovered which crystallizes to a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05284838 |
|---|
| 출처 데이터셋 | uspto-grants-1994_02 |
|---|
| ORD ID | ord-90187e1883424e1999df727823c3ea76 |
|---|
| 출처 메모 | uspto-grants-1994_02 |
|---|
