Water → 1-(3,5-Dimethylphenoxy)-2-propanone oxime

HRID 1975542

반응식

HRID 1975542 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[C:11]([CH3:13])[CH:12]=1)[O:5][CH2:6][C:7](=O)[CH3:8].S(O)(O)(=O)=O.[NH2:19][OH:20].C(=O)([O-])O.[Na+].O>C(O)C>[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[C:11]([CH3:13])[CH:12]=1)[O:5][CH2:6][C:7](=[N:19][OH:20])[CH3:8]

참가 물질

6

반응물 4

HCID 962WaterHCID 159255Hydroxylamine, sulfate (1:1)HCID 3088301-(3,5-Dimethylphenoxy)propan-2-oneHCID 516892Sodium Bicarbonate

생성물 1

HCID 731208521-(3,5-Dimethylphenoxy)-2-propanone oxime수율 155.2%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

10.0 Grams (56 mmol) of 1-(3,5-dimethylphenoxy)-2-propanone was dissolved in 50 ml of ethanol, and 5.53 g (34 mmol) of hydroxylamine sulfate and 5.66 g (67 mmol) of sodium hydrogencarbonate were added. And, the resultant mixture was stirred at room temperature for 4 hours, and 50 ml of water was added. Ethanol was distilled off under reduced pressure, and the resultant solid precipitate was recovered by filtration, washed with water and dried to give 10.2 g of 1-(3,5-dimethylphenoxy)-2-propanone oxime (yield 92%).

후처리

  1. distillationEthanol was distilled off under reduced pressure
  2. filtrationthe resultant solid precipitate was recovered by filtration
  3. washwashed with water
  4. customdried

출처 및 근거

ORD 기록
ord-da762cef694e4036a3a81a3b60f80298
출처 데이터셋
uspto-grants-1994_02
특허 번호
US05286905

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