Potassium Carbonate → 1-Bromo-4-(7-bromoheptylthio)benzene

HRID 1977284

반응식

HRID 1977284 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.[Br:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]Br.C(=O)([O-])[O-].[K+].[K+]>O>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][Br:9])=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 660494-BromothiophenolHCID 783091,7-Dibromoheptane

생성물 1

HCID 219974831-Bromo-4-(7-bromoheptylthio)benzene수율 65.6%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of 4-bromobenzenethiol (6 g), 1,7-dibromoheptane (16.37 g), and potassium carbonate (8.77 g) in dimethylformanide (30 ml) was stirred at room temperature for 5.5 Hours. The reaction mixture was pulverized with water and extracted with ethyl acetate. The organic layer was separated, washed with brine, dried over magnesium sulfate and evaporated under reduced pressure to give 1-bromo-4-(7-bromoheptylthio)benzene (7.62 g).

후처리

  1. extractionextracted with ethyl acetate
  2. customThe organic layer was separated
  3. washwashed with brine
  4. dry with materialdried over magnesium sulfate
  5. customevaporated under reduced pressure

출처 및 근거

ORD 기록
ord-f5acaecee15e4334b0b5c03c3d76edc2
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06232290B1

연결된 노트

불러오는 중…