Triethylamine → 1-{4-[(Prop-2-en-1-yl)oxy]phenyl}-1H-pyrrole-2,5-dione
반응식
[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15](=[O:16])[CH2:14][CH:13](Cl)[C:12]2=[O:18])=[CH:7][CH:6]=1)[CH:2]=[CH2:3].C(N(CC)CC)C>ClCCl>[CH2:1]([O:4][C:5]1[CH:6]=[CH:7][C:8]([N:11]2[C:15](=[O:16])[CH:14]=[CH:13][C:12]2=[O:18])=[CH:9][CH:10]=1)[CH:2]=[CH2:3]참가 물질
4
반응 조건
- 온도
- 10 °C
실험 절차
N-(4-Allyloxyphenyl)chlorosuccinimide (265.5 g, 1 mole) was dissolved in dichloromethane (1300 ml) and cooled to 10° C. Triethylamine (101 g, 1 mole) was added in 10 min and the reaction was stirred for 10 min. The reaction mixture was washed with 1M hydrochloric acid and dried over sodium sulfate. The organic solvent was removed under reduced pressure and the solid was recrystallized from methanol.
후처리
- washThe reaction mixture was washed with 1M hydrochloric acid
- dry with materialdried over sodium sulfate
- customThe organic solvent was removed under reduced pressure
- customthe solid was recrystallized from methanol
출처 및 근거
- ORD 기록
- ord-b6c8e41bcc6b4d1a955957c5e26ebae3
- 출처 데이터셋
- uspto-grants-2001_05
- 특허 번호
- US06232430B1
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